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KMID : 0363020110410050242
Journal of Korean Academy of Periodontology
2011 Volume.41 No. 5 p.242 ~ p.247
The effect of fibronectin-coated implant on canine osseointegration
Kim Sung-Tae

Myung Woo-Chun
Lee Jung-Seok
Cha Jae-Kook
Jung Ui-Won
Yang Hyeong-Cheol
Lee In-Seop
Choi Seong-Ho
Abstract
Purpose: The purpose of this study was to characterize the osseointegration of the fibronectin-coated implant surface.

Methods: Sand-blasted, large-grit, acid-etched (SLA) surface implants, with or without a thin calcium phosphate and fibronectin coating, were placed in edentulous mandibles of dogs 8 weeks after extraction. All dogs were sacrificed forhistological and histomorphometric evaluation after 4- and 8-week healing periods.

Results: All types of implants were clinically stable without any mobility. Although the bone-to-implant contact and bone density of the SLA implants coated with calcium phosphate (CaP)/fibronectin were lower than the uncoated SLA implants, there were no significant differences between the uncoated SLA surface group and the SLA surface coated with CaP/fibronectin group.

Conclusions: Within the limits of this study, SLA surfaces coated with CaP/fibronectin were shown to have comparable bone-to-implant contact and bone density to uncoated SLA surfaces.
KEYWORD
Biocompatible coated materials, Bone density, Calcium phosphate, Dental implants, Fibronectins
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